Tag Archives: work-life balance

That Didn’t Last Long

My previous post did not age well.  After a gorgeous start, Autumn has come to a bitter end here in East Lansing—many weeks before the official start of Winter.

We had several inches of snow two nights ago, followed by extreme cold last night.

It is quite beautiful, though, as you can see in the first picture below.  But many of the local sidewalks are a hazardous mess—ice interspersed with rock-hard lumps of snow—and the snow-covered lawns are now getting covered with leaves that hadn’t yet fallen, as you can see in the second picture.

Snow in November 2019

Leaves on top of early snow

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Autumn at MSU

A lovely autumn morning in East Lansing.

Maple MSU Oct 2019Red Cedar foliage Oct 2019

Next week I’ ll get to discuss a couple of my all-time favorite papers – Chao and Levin on colicins, and Lieberman et al. on parallel evolution in an epidemiological setting – with graduate students in our Integrative Microbial Biology course.

That is all.  Happy Friday, and have a great weekend.

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Hat Trick

This past weekend Madeleine and I attended the annual meeting of the American Academy of Arts & Sciences in Cambridge, Massachusetts. The Academy was founded in 1780 by John Adams and several dozen other scholar-patriots “to cultivate every art and science which may tend to advance the interest, honor, dignity, and happiness of a free, independent, and virtuous people.”

It was an especially exciting meeting for us because we got to see three of our dear friends inducted as new members:  Paul Turner and, as International Honorary Members, Valeria Souza and Sebastian Bonhoeffer.  All three of them signed the membership book, putting their “John Hancocks” alongside those of distinguished artists, scientists, scholars, and leaders (including the John Hancock) from the past 239 years, while Madeleine and I celebrated with their spouses and families.

I’ve known Paul, Valeria, and Sebastian for decades.  Paul was a graduate student in my group at UC-Irvine, and then he moved with me to MSU, receiving his PhD in 1995. For his dissertation, Paul studied issues related to vertical and horizontal transmission in bacteria, including the roles of density- and frequency-dependent selection. Paul is a professor at Yale University, where he and his team study the evolution and ecology of viruses, including some that can specifically target antibiotic-resistant bacteria and have been used to cure life-threatening infections.

Valeria was a postdoc in my group, also first at UCI and then again at MSU. She worked with Paul on a fascinating, but challenging, experiment to investigate the effects of horizontal gene transfer on the speed of adaptive evolution in bacteria. Valeria is a professor at Universidad Nacional Autonoma de Mexico, where she and her group conduct research and work with the local community, governmental agencies, and nonprofits to conserve the Cuatro Cienegas basin, a biologically unique and fragile system of oases in the Chihuahuan Desert.

Sebastian and I met at Oxford University in 1993, where he was a graduate student and I was on sabbatical. We collaborated on a theory project that examined the hypothesis that pathogens with long-lived propagules would evolve to be more virulent. More recently we’ve taught together in the Guarda (Switzerland) summer course on evolutionary biology. Sebastian is a professor at ETH Zurich, where he and his team construct and analyze mathematical models of population dynamics to understand, for example, the pathogenesis and spread of HIV and other viruses.

Besides being creative and talented scientists, Paul, Valeria, and Sebastian are three of the nicest people around. I’ve been incredibly fortunate not only to work with them, but also to know them as close friends.

And there were so many other outstanding inductees, some of whom I’ve also known for many years including microbial ecologist Jo Handelsman (University of Wisconsin), theoretical ecologist Mercedes Pascual (University of Chicago), evolutionary biologist Mark Rausher (Duke University), plant biologist Detlef Weigel (MPI Tubingen), and evolutionary biologist Kelly Zamudio (Cornell University).

Each of the 5 “classes” had a speaker give a short talk to all the inductees and their families. Representing the Biological Sciences, Jo Handelsman gave an impassioned talk “On the importance of soil.” It’s something almost everyone takes for granted, and yet fertile topsoil is incredibly valuable, it’s disappearing in many areas, but it can be preserved and even enhanced with improved agricultural practices. Representing Public Affairs, Business, and Administration, Sherrilyn Ifill (NAACP Legal Defense Fund) gave a clarion call to fix American democracy.

The evening before the induction ceremony there were artistic performances and presentations by several new members including jazz pianist, composer, and singer Patricia Barber.  The morning after the induction included a performance by, and discussion with, the incredible playwright, filmmaker, and actress Anna Deavere Smith, who performed and described how she constructs her amazing one-woman shows.

Throughout all the events, the staff of the American Academy of Arts & Sciences were superbly organized and warmly welcoming.

[Paul Turner’s family in the theater just before he signs his name into the book of members of the American Academy of Arts & Sciences]

Paul's family at AAAS 2019

[Valeria Souza signing the book, with Paul Turner just behind her and waiting his turn]

Valeria signing, Paul just behind, AAA&S 2019

[With Valeria Souza and her family following the induction ceremony]

Valeria and family at AAAS 2019

[Sebastian Bonhoeffer and his wife Hanna (next to me) with Madeleine (next to Sebastian) and me the evening before the induction ceremony]


[Yours truly along with Mercedes Pascual, Paul Turner, and Sebastian Bonhoeffer]

AAAS 2019 Mercedes, Paul, Sebastian and me

[Sebastian, Paul, Valeria, me, and Luis Eguiarte (Valeria’s husband, and also a superb evolutionary plant biologist]

Sebastian, Paul, Valeria, me, Luis AAA&S 2019

[Paul and I compare our biologically themed ties.]

Paul and me at AAA&S 2019

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Half Life

Today marks a unique day for the LTEE and me.

The LTEE started on February 17, 1988.  That was 11,517 days ago.

I was born on August 13, 1956.  That was 23,034 days ago.

That means that the LTEE is now half as old as I am.

To put it another way, I’ve spent half a lifetime on the LTEE.

Well, that’s not quite the right way to put it, since I’ve done a few other things during that time. Like raising a family—with a lot of help.  And a lot of other science, also with a lot of help, not to mention all the work of so many students and collaborators on the LTEE itself.

And unlike a radioactive isotope, the bacteria haven’t been decaying—they’ve been getting better and better at living in their flask-worlds.

My hope is that this long-term evolution experiment will continue for a long time. A very long time. For a lot longer than my own lifetime.

Here are a couple of photos from around the time the LTEE started. The first one shows Madeleine and me camping near Joshua Tree National Park in the summer of 1987, at the annual retreat of the UC-Irvine EEB department, and only a couple months before the birth of our youngest. The next one shows me snuggling with my three kids in early 1989.


How time flies. Luckily, though, I get to snuggle with my three grandkids now.

Bacterial generations. Human generations. Growing, evolving, and learning.






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Coach Izzo and me

Chalk up another great year for the Michigan State men’s basketball team and coach Tom Izzo. The Spartans were co-champions of the Big10 and won the conference’s grueling tournament. And in the NCAA’s March Madness, they made it all the way to the Final Four, knocking out the top-seeded team in the process.

Being a fan of this team got me thinking: Coach and I have a lot in common. We’ve both been doing our jobs, mostly at MSU, for a long time. Coach Izzo came here as a part-time assistant in 1983, becoming head coach in 1995. I was on the faculty at UC-Irvine starting in 1985, before moving here in 1991.

But the real similarities are deeper and more important:

First and foremost, we’ve both been fortunate to be surrounded by talented and hard-working students who listen to our ideas, experiment with them, develop them in their own ways, and translate them into meaningful outcomes—winning big games and making new discoveries.

That’s not to say there aren’t frustrations along the way: games lost, grants and papers rejected, grinding practice on the court and repetition in the lab, and even occasional conflicts. But our students are usually resilient—they overcome those setbacks and frustrations, and they go on to productive lives as players and coaches, researchers and teachers, and other careers as well.

We also both had mentors who helped us start our own careers. In Coach Izzo’s case, one mentor was Jud Heathcote, the previous head coach who hired him as an assistant. My mentors included my doctoral advisor, Nelson Hairston, and my postdoctoral supervisor, Bruce Levin. Coach Izzo and I also had friends who helped shape our careers early on: Steve Mariucci, who went on to become an NFL coach; and Phil Service, who did important work on life-history evolution.

Coach Izzo and I also both benefitted, I think, from early successes—again, largely due to our students—that helped establish our reputations, allowing us to retain our jobs and thrive by recruiting more talented, hard-working students. For Tom Izzo, it was players like Mateen Cleaves, Charlie Bell, and Mo Peterson who took the Spartans to the Sweet 16 in his 3rd year as head coach and to the Final Four the next year, and who won the 1999-2000 National Championship. For me, the early students included Judy Bouma, Felisa Smith, John Mittler, Mike Travisano, Paul Turner, and Farida Vasi, and postdocs Toai Nguyen and Valeria Souza.

Coach Izzo has also had assistant coaches and staff, who I imagine do a lot of the heavy lifting. While some might eventually become head coaches of their own teams, many others labor in relative obscurity. In a similar vein, I’ve had outstanding lab managers including Sue Simpson, Lynette Ekunwe, and—for over 20 years, before retiring last year—Neerja Hajela.

Coach Izzo and I have both had deep benches—students who helped the team succeed without being in the limelight themselves. For Coach Izzo, they include the walk-ons and others who see limited action in games, but who compete against the starters every day in practice, helping everyone become even better. I think of three undergraduates who joined my lab when it was just getting started in Irvine (all Vietnamese refugees, by the way) who asked if they could work in my lab. Trinh Nguyen, Quang Phan, and Loan Duong prepared media and performed experiments like some incredible three-brained, six-handed machine, setting a high standard for everyone who followed in their footsteps.

Coach Izzo and I are nearly the same age. Retirement might be easier, but neither of us is ready for that. It’s too much fun when you’ve got talent to encourage and guide like Cassius Winston, Joshua Langford, Nick Ward, Xavier Tillman, and Aaron Henry—and on my team Jay Bundy, Kyle Card, Nkrumah Grant, Minako Izutsu, and Devin Lake.

Of course, there’s more that Coach Izzo and I have in common—we were lucky to be born into circumstances that allowed us to pursue our dreams without the obstacles that many others face.

Last but not least, Coach Izzo and I have had supportive partners who’ve accepted our peculiar obsessions and the long hours and frequent travel that our work entails.

Go Green! Go Students!!

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We interrupt this program

We interrupt our irregularly scheduled blogging to wish the long-term evolution experiment a very fit 31st birthday!

Here are two pictures of graduate student Kyle Card doing today’s transfers, and thereby starting off the next year of their evolutionary journey.

Kyle Card setting up LTEE transfers on 31st birthday

Kyle Card transfers LTEE on 31st birthday

Today’s entries in the LTEE notebook are shown below.

LTEE notebook on 31st birthday

We also had a visitor who picked up some strains from the freezer over the weekend, and who left us a note on the lab’s whiteboard.

Zack left note 23-Feb-2019

We ate a Galapagos-themed cake, shown below, a couple of weekends ago when we celebrated the February birthdays of Charles Darwin, Abe Lincoln, and the LTEE.

Darwin cake 2019

Thank you Kyle, and thanks to everyone who has ever performed transfers and/or done research on the LTEE lines.

Last but not least, here’s a lovely post by Roberto Kolter at Small Things Considered wishing the LTEE a happy birthday!


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Fun in Philadelphia

Madeleine and I just spent a few magical days in Philadelphia, where I was inducted into the American Philosophical Society. While I had heard of the APS, and knew it had a long history, I didn’t know very much about it until a few years ago, when I heard about some colleagues being elected.

The APS was founded in 1743 by Benjamin Franklin, making it the oldest learned society in the United States, and making this the 275th anniversary year. George Washington was a member. Thomas Jefferson was a member. In fact, Jefferson was President of the APS while he was also serving as Vice President and President of the United States. Barrack Obama is another member. In other words, there’s a bit of history associated with the APS.

Our hotel was almost next door to the APS, including the Benjamin Franklin Hall (with the auditorium where the meeting was held) as well as the museum and library. (More on those later.) Here’s the view from our hotel room the evening we arrived. Yes, that’s Independence Hall, where the Declaration of Independence was approved on July 4, 1776.

Independence Hall at night

The highlights of the meeting for me are almost beyond description, but here’s an attempt.

The people: From colleagues across all fields to the staff and officers of the APS, everyone was exceptionally welcoming to Madeleine and me. (Partners and spouses are as much a part of the meeting as the members.) I got to see some longtime friends from the field of evolutionary biology including David and Marvalee Wake; I got to chat with people from other fields who I’ve met before, but rarely get to see, including population biologist Joel Cohen and geneticist Michael Young; I got to meet people for the first time including APS President Linda Greenhouse, an expert on the Supreme Court, and her husband Eugene Fidell, who works in military law. And many other warm, welcoming, and interesting people.

The talks: There were several talks each day, across a wide range of fields, and they were uniformly lively and interesting. You can see the full program here, and I’ll just mention some of them that especially caught my fancy. Two talks on the history of the US census (Margo Anderson) and on political fights over its implementation (Kenneth Prewitt). Three talks on new technologies used to give voice to the voiceless (Rupal Patel), on interpreting interactions between police and motorists (Dan Jurafsky), and on future cameras that can reveal with extraordinary resolution a fingerprint on an object in a still life photo or capture the image reflected in a subject’s gaze (Shreer Nayar). Toni Morrison received the 2018 Thomas Jefferson Medal for Distinguished Achievement in the Arts, Humanities, and Social Sciences; while she could not attend, a moving letter of acceptance was read on her behalf. Bryan Stevenson received the 2018 Benjamin Franklin Medal for Distinguished Public Service and he gave an inspiring, hard-hitting, beautiful, and moving talk about his childhood and his life’s work for social justice, emphasizing the importance of proximity, memory, empathy, and persistence. You can—and really should—hear his talk on memory and justice. (The award starts at ~35 minutes, followed by a short acceptance speech, and then his hour-long talk at ~42 minutes. Set aside the time; you won’t be disappointed.)

The Treasures: Wow. The APS library includes over 13 million manuscripts, many of extraordinary historical and scientific importance. The amazing staff of the APS, including Library Director Patrick Spero and Museum Director Merrill Mason, pulled out some of the original treasures for us to see. Among them: Thomas Jefferson’s final draft of the Declaration of Independence, with his marginal comments showing the changes that were made (to Jefferson’s consternation) in order to secure approval from Congress. The only document signed by the first four US Presidents: Washington, Adams, Jefferson, and Madison. All four were members of the APS, and they signed pledges to contribute financially to a cross-continental scientific survey of the flora by André Michaux, a French botanist. Although this expedition was eventually stymied by politics, it was a precursor to Lewis and Clark. Speaking of which, another treasure we got to see was one of the journals of the Lewis and Clark expedition, with a beautiful, tiny, hand-drawn map of Cape Disappointment. On the science side, we saw Charles Darwin’s draft of the title page of The Origin of Species, which he had originally titled “An abstract of an Essay on the Origin of Species and Varieties Through Natural Selection.” We also got to see a notebook of the physicist John Wheeler, with his illustration of gravitational collapse producing a “black hole”—this was especially exciting because Wheeler was a mentor of Madeleine’s stepfather, also a theoretical physicist. As I said, wow! The APS has some of these items on display at their Museum, and you can see some of these treasures online as well.

Another treasure: Another great pleasure was spending time with my wonderful friend and MSU colleague Jack Liu. Jack holds the Rachel Carson Chair in Sustainability, and his work focuses on the complex interactions between people and the environment—from protecting pandas and their special habitat in China, to the effects of divorce on energy consumption in American households. As we rode together to and from airports, I learned Jack’s own inspirational story: from a tiny village in China to becoming the first member of his family to attend college; his experience learning English almost from scratch while a doctoral student at the University of Georgia; and becoming the first person from MSU ever elected to the American Philosophical Society.

Jack and me at APS Nov 2018

[Here’s a picture of Jack Liu and me standing below portraits of Franklin and Washington in the APS Auditorium.]

Signing the book at APS

[Here’s a picture that Jack took of me “signing the book” during my induction into the APS.]

Greeting from Linda Greenhouse

[This one, which Jack also took, shows me being officially welcomed by Linda Greenhouse, the APS President, after Robert Hauser (at left), the Executive Officer, has read a statement about my work.]


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