The LTEE has run for over 30 years and almost 70,000 generations. It’s time to shut it down, as of today.
It’s been a hell of a lot of work, and we have almost nothing to show for it. As some astute commentators have noted around the web, the creatures in the flasks are still just bacteria—creatures, just as they were created.
If you read the first LTEE paper*, you’ll see we predicted the bacteria should become yeast by about 5,000 generations, nematodes at 15,000 generations or so, and fruit flies by 30,000 generations, maybe 35,000 at the outside.
After that, we’d have to stop the experiment anyhow, because we wouldn’t be able to freeze and bring them back alive any longer.
Plus, we’d have to get IRB approval for human experimentation if we ran it much past 50,000 generations.
Well, we’ve given the LTEE all this time, and still … they’re just bacteria. I guess we’ve proven that Charles Darwin was wrong after all.
As an astute reviewer pointed out when we submitted that first paper, “I feel like a professor giving a poor grade to a good student …” I should’ve listened and quit way back then. It would’ve saved everyone a lot of time and effort.
Now it’s going to be a hell of a lot of work next week emptying the freezers and autoclaving all those samples.
*Lenski, R. E., M. R. Rose, S. C. Simpson, and S. C. Tadler. 1991. Long-term experimental evolution in Escherichia coli. I. Adaptation and divergence during 2,000 generations. American Naturalist 138: 1315-1341.
8 responses to “Thirty years is enough”
Well boss, it was only a matter of time before this moment came. It’s been a fun run, but if I’m honest, it’s really more than a bit of a relief. It was getting hard to keep a straight face when telling people what’s been found in the experiment. I’ll have drafts of retractions for the first batch of papers to you later today.
What would be for us who are inspired by this work and running the same evolution experiment across the globe like me!
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Sunday being both Easter and April 1 made me miss many of this years fools; doing some catch-up reading now.
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If it took 70,000 generations to lead to the evolution of this legitimately funny Aprils fools joke, then I say it was time and resources well spent! I hope your next endeavor is more successful 🙂 /s